Mother and son.

Crowley: The point is, you hated me.

Rowena: Oh please...

Crowley: You said you'd be back in a flash, and then you disappeared. I was eight years old! EIGHT!

Rowena: Oh, now you're being dramatic.

Crowley: I didn't even have a father!

Rowena: Of course you had a father! You were just conceived during a winter solstice orgy and it's not like I was taking names.