Mass Effect and Ducktales? Oh fuck yes that sounds so stupid I love it

Mass Effect and Call the Midwife.

That's a very interesting direction for a sci-fi show to take.

Genshin Impact: Leverage

this can only be amazing

The Great Persona 5 Baking Show

that would work far better than it reasonably should.

New X-Files Snap

Stargate: 2033 or Metro: SG-1.